The Heart Smart Cellular Energy Enhancer

Do you remember what it felt like to leap out of bed in the morning when you were a kid … especially in the summer when you greeted each day with energy and enthusiasm to spare? Well, imagine how much you’d accomplish today if you had 50% of that energy.

You’d have the stamina you need to achieve your goals, and you’d feel pretty good at the end of the day.

It could be that you need to supplement your diet with D-ribose. We’re hearing more and more about how ribose is a natural, potent energy enhancer, which just might make a difference in how you greet each day.

What is ribose?

D-Ribose (also known as ribose) is a simple sugar produced in the body that is used by all living cells. It is part of the building blocks that form DNA and RNA molecules, and is one of the crucial ingredients in the production of adenosine tri-phospate (ATP).

What is ATP?

In a nutshell, it’s called the “energy currency” of all cells. It’s the body’s primary energy-carrying molecule that assists in the conversion of nutrients into usable energy, which enables your body to function.

During vigorous exercise or times of stress, large amounts of ATP can be depleted in the heart and skeletal muscles. The problem is your heart, muscles, and other organs and tissues do not make ribose very quickly, and it is not stored in the tissues and cells. Additionally, when your heart and muscles are stressed, ribose levels can be so low that they have a difficult time recovering.

The good news is that ribose supplementation stimulates energy synthesis, allowing tissues to regenerate energy stores, giving them the boost they need to function efficiently … so that you have the energy you need to do what you want to do, while feeling good.

Why take supplemental ribose?

Lack of energy is the number one health complaint heard by doctors. The food you eat, the supplements you take, and the amount of exercise and quality of sleep you get all affect your ability to produce energy at the cellular level. But oxidation (free radical production), stress, overwork, and the quality of the air we breathe are some of the biggies that deplete our reserves and energy levels.

Whether you just want an energy boost or you are an athlete wanting to achieve your goal … whether you suffer from chronic fatigue syndrome or congestive heart failure and heart disease, studies show that you can benefit from adding supplemental ribose to your health regimen.

Who can benefit from D-ribose supplementation?

Everyone needs D-ribose because it is an essential ingredient in stimulating natural energy production. It is especially beneficial to older people, athletes, weekend warriors, and those dealing with chronic or unexplained fatigue, fibromyalgia, coronary artery disease, and congestive heart failure.

Benefits

Research has shown that D-ribose may hold numerous benefits for:

  • Heart disease
  • Chronic muscle disease
  • Aging
  • Chronic fatigue syndrome
  • Fibromyalgia
  • Athletic performance and recovery

How does D-ribose work?

The form of D-ribose that the body utilizes is called 5-phosphoribosyl-1-pyrophosphate (PRPP), which regulates the metabolic pathway that synthesizes energy compounds in all living tissue. This pathway is called the Purine Nucleotide Pathway (PNP). But if the body doesn’t have enough PRPP—or D-ribose—energy synthesis slows and tissue recovery is delayed. It is then crucial that ribose levels be replaced.

Scientists have found that supplemental D-ribose can rapidly stimulate the metabolic pathway used by the body to replenish these energy levels, restoring ribose levels in nerves and muscles. This in turn has a positive effect on ATP production in all muscles, especially the heart.

The general theory is that when a person has heart disease, ATP is degraded—which then means there is less energy for the heart to function properly. The heart’s ability to re-synthesize ATP is then limited by the availability of D-ribose. In support of this theory, recent studies have shown that ribose helps patients with myocardial ischemia and exercise-induced angina.1

D-ribose supplementation:

  • Increases the rate of ATP and energy recovery after strenuous exercise, stress, and overwork
  • Shortens the time needed by heart and muscle tissue to replace energy that is lost through stress, exercise, and overwork
  • Helps the heart and muscles maximize energy recovery
  • Increases stamina and endurance, and reduces fatigue

D-Ribose and heart disease

“Congestive heart failure is one of the most common reasons people 65 and older go into the hospital.”

Heart disease is the number one killer in America. According to the American Heart Association, it claimed 871,500 lives in 2004 (36.3 percent of all deaths or 1 of every 2.8 deaths).2  There is good news though. Numerous scientific and clinical studies have shown that D-ribose can help to restore energy and function to the heart. It is especially helpful to those with ischemic cardiovascular disease3—lack of blood flow and oxygen to the heart muscle—and congestive heart failure (CHF).

Congestive heart failure is one of the most common reasons people 65 and older go into the hospital. It can take years for heart failure to develop. So if you don’t yet have it but are at risk for it, adding D-ribose to your health regimen would be an excellent start to improve your health.

What happens when the heart muscle loses its umpf?

When the heart muscle loses energy, first it suffers a loss of diastolic function. This is the relaxation phase when the heart fills with blood for the next heartbeat. When diastolic function is compromised, less blood circulates to the body during each beat, and can lead to hypertrophy; a thickening and expansion of the heart muscle. Additionally, there is inadequate oxygen circulating throughout the body, which causes the heart to overcompensate by using energy faster than it normally does. This results in a depletion of cellular energy reserves. Ultimately, it becomes a vicious cycle in which a loss of cardiac energy leads to a loss of heart function.

“An increased cellular demand for ATP can severely affect the body’s biochemistry, which may take several days to recover or may not recover at all in cases of chronic ischemia.”

Congestive heart failure is often the result of chronic diastolic dysfunction. Symptoms include shortness of breath, loss of exercise capacity, and overwhelming fatigue.

Research has also shown that intense endurance exercise puts a big strain on the heart, contributing to a loss of diastolic heart function that can continue for weeks or months following an athletic event such as a marathon or triathalon. An increased cellular demand for ATP can severely affect the body’s biochemistry, which may take several days to recover or may not recover at all in cases of chronic ischemia. Supplemental ribose, however, can enhance the recovery of heart and muscle ATP levels.4

Scientific studies

A study of 15 patients with chronic coronary artery disease and congestive heart failure who were given D-ribose for three weeks found that the supplement improved diastolic functional parameters and enhanced their quality of life.5

A German study demonstrated that D-ribose supplementation is effective in increasing the heart’s tolerance to ischemia. Twenty patients diagnosed with coronary artery disease completed two treadmill tests on consecutive days to establish pain thresholds for each patient. The researchers then gave each patient 60 grams of ribose per day for three days, plus another treadmill test. The patients who took ribose were able to walk further before experiencing pain than those given the placebo.6

“D-ribose is a powerful fatigue fighter—20% of Americans suffer from fatigue that interferes with their normal life.”

Chronic Fatigue Syndrome (CFS)

Chronic fatigue syndrome is the diagnosis used to describe fatigue that lasts more than six months and can’t be attributed to any other illness. It affects more than one million people in the U.S. Although it is more common in people in their 40s and 50s, it can occur in any age, gender, ethnicity, or socioeconomic group. The symptoms usually include four or more of the following:

  • Sore throat
  • Impaired short-term memory and/or concentration
  • Tender lymph nodes
  • Joint pain without swelling or redness
  • Muscle pain
  • Headaches
  • Unrestful sleep

Scientific studies

Fibromyalgia and chronic fatigue syndrome are debilitating syndromes that are often associated with impaired cellular energy metabolism. An uncontrolled pilot study of 41 patients was done to see if ribose could improve symptoms of fibromyalgia and/or chronic fatigue.

66% of the patients with a diagnosis of fibromyalgia and/or chronic fatigue syndrome who took D-ribose showed an improvement in their energy, sleep, mental clarity, pain tolerance, and sense of well-being. Among these patients, their energy levels increased about 45% and they experienced an average 30% boost in overall well-being. The researchers concluded that ribose significantly reduced clinical symptoms in these patients suffering from fibromyalgia and chronic fatigue syndrome.7

An article that appeared in the 2004 issue of Journal of Pharmacology highlighted a case study about a fibromyalgia patient who added supplemental D-ribose to her regimen and subsequently had a significant decrease in symptoms.8

Ribose and athletic performance

Free radicals are produced during intense exercise. Based on this theory and the theory that ribose is present in ATP, and that increasing adenine nucleotide availability may enhance high intensity exercise capacity, ribose supplements have been popular with athletes and active individuals for many years. However, there have only been a few clinical studies done that prove this theory.

Scientific studies

In one study D-ribose (10g/d) was shown to increase athletic performance and muscular strength in healthy, young male recreational bodybuilders after four weeks. No significant changes in their body composition were noted, and there were no changes at all found in the men who took a placebo.9

Another study of seven healthy men who did two ergometric sessions (stress tests to determine physiology) on a bicycle to exhaustion at a one-week interval indicated that D-ribose improved the efficiency of their energy production.

Before the second test, the men took seven grams of ribose, which resulted in a reduction of urinary MDA—an indicator of oxidation and lower heart rates, when compared to the group who didn’t take the D-ribose supplement.10

What should I look for in a D-ribose supplement?

Look for a D-ribose product that contains pure ingredients in an easy-to-use powder form. It should contain proven amounts that have shown to be effective in research studies. Dosage in these studies typically ranged between 5-60 grams daily.

Conclusion

Most tissues in the body—especially the heart—are unable to produce ribose fast enough to restore levels once they’ve been depleted. It’s a matter of supply and demand. Just as a car battery needs enough fluid to keep it charged and running, your body needs plenty of ribose to help it produce the ATP that supplies cells with an energy current.

So whether you suffer from chronic fatigue syndrome or congestive heart failure or heart disease … or whether you just want an energy boost or are an athlete wanting to achieve your goals, consider adding supplemental D-ribose to your health regimen for the energy boost that might make a big difference in your life.

Slow Aging with Nicotinamide Mononucleotide (NMN)

Complements of the Phytocopeia Natural Products Formulary

What is Nicotinamide Mononucleotide?

Nicotinamide Mononucleotide or NMN is an organic molecule advertised as a kind of “Fountain of Youth” natural supplement. The reason is based on how it acts as a precursor to nicotinamide adenine dinucleotide or NAD. 

NAD boosts cellular energy production (ATP), promote efficient metabolism, improves sleep and recovery, and benefits hundreds of other enzymatic reactions crucial to everyday life.

We also lose NAD as we age, and scientists hypothesize that increasing NAD levels could help delay ageing. [1]

Food Sources of Nicotinamide Mononucleotide

Since we can’t exactly eat NAD, primarily because the human body wasn’t designed to absorb NAD through digestion, the next best thing is to get NMN from food sources. Some of these sources are edamame, broccoli, cucumbers, cabbage, avocado, and tomatoes.

While getting NMN from our diet is possible, it’s not very efficient since NMN can only be found in trace amounts. This is where supplementation comes in.

Performance and Health Benefits of Taking Nicotinamide Mononucleotide

So, what does supplementing NMN do for you? 

Nicotinamide Mononucleotide helps slow down aging

The biggest reason why NMN supplements are flying off shelves is how it was studied as an anti-aging supplement. As mentioned, it works by boosting NAD levels, a compound that naturally declines with age. Therefore, boosting NAD levels can indirectly lead to a longer lifespan. [2]

It also seems to work on other factors that affect aging such as telomere length – a tail of our DNA that shortens as we age – and sirtuin activity – a family of molecules that exhibit antioxidant properties, fight cellular aging, lower DNA damage, and is involved in complex anti-aging processes.

Nicotinamide Mononucleotide Improves quality of life

Some scientists believe taking NMN supplements can help with slowing aging as well as improving our overall health, especially when it comes to lowering cholesterol and triglyceride levels. It’s also been highlighted to promote physical activity.

Other studies note that it can possibly provide better eyesight for those who have trouble reading without glasses. 

These findings demonstrate that NAD+ biosynthesis is essential for vision, provide a foundation for future work to further clarify the mechanisms involved, and identify a unifying therapeutic target for diverse blinding diseases.[3]

Nicotinamide Mononucleotide Promotes heart health

Some studies show NMN supplements help restore damaged heart tissue as well as reverse blood vessel damage caused by aging. These resulted in better blood flow as well as a stronger heart overall. 

In the present study, 8 weeks of NMN supplementation restored a marker of arterial SIRT1 activity and ameliorated age‐associated endothelial dysfunction and large elastic artery stiffening in male C57Bl/6 mice.[4]

Limitations

While Nicotinamide Mononucleotide supplementation seems promising, it has to be noted that all the studies used and all the positive results were derived from mostly using mice as subjects.

Many studies regarding supplements used animal subjects and drew positive results in humans, but that’s not to say it works the same way all the time. 

Summary

Nicotinamide Mononucleotide is an important molecule known to promote chemical reactions and processes inside the body that help fight aging.

You can always supply the body with Nicotinamide Mononucleotide from dietary sources, but the most efficient way is to take Nicotinamide Mononucleotide supplements.

Studies show Nicotinamide Mononucleotide supplementation has great benefits with regards to slowing aging as well as overall quality of life and heart health. While the majority of studies do revolve around mice subjects, test results are promising and shouldn’t discourage consumers.

References:

  1. Poddar SK, Sifat AE, Haque S, Nahid NA, Chowdhury S, Mehedi I. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019;9(1):34. Published 2019 Jan 21. doi:10.3390/biom9010034
  2. Kawamura T, Mori N, Shibata K. β-Nicotinamide Mononucleotide, an Anti-Aging Candidate Compound, Is Retained in the Body for Longer than Nicotinamide in Rats. J Nutr Sci Vitaminol. 2016;62(4):272-276
  3. Lin JB, Kubota S, Ban N, et al. NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice. Cell Rep. 2016;17(1):69–85. doi:10.1016/j.celrep.2016.08.073
  4. de Picciotto NE, Gano LB, Johnson LC, et al. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell. 2016;15(3):522–530. doi:10.1111/acel.12461

Oral Chelation—The Strongest Natural Treatment for Your Heart, Arteries, Memory, and More!

Heart and Cardiovascular

Oral chelation therapy is a potent, safe, inexpensive and virtually risk-free blood circulation treatment.

What heart disease really does to your body … and how Oral Chelation can reverse it

If you or a loved one suffers from any form of CVD, here is the simple truth about how this disease operates. What the public tends not to realize—and what your doctor has likely failed to explain to you—is that the primary precursor to heart disease, atherosclerosis (hardened arteries) is not a localized problem. It’s a systemic condition. In other words, atherosclerosis is present not only in the coronary arteries, but also in the brain, lungs, kidneys, and legs.

What’s more, the blockages that lead to atherosclerosis can occur not only in the larger vessels—the vessels that can be seen and manipulated by surgeons and cardiologists—but in the smaller blood vessels as well. It is in these smaller blood vessels, the capillaries, that the oxygen exchange to the tissues takes place. You can protect that critical lifeline of oxygen that feeds and sustains the organs and tissues throughout your body—including your heart. There exists today a treatment that removes plaque and restores blood flow throughout the entire arterial system, treating the micro as well as the macro vessels. It’s called EDTA chelation, available via intravenous and oral supplementation. You should consider chelation therapy—safe, inexpensive, and proven effective—if you have a family history of CVD or existing CVD. You should also consider chelation if you simply want to do everything within your power to prevent CVD … and the potentially disastrous effects of the conventional medical treatments for this deadly disease.

Traditional medicine approaches heart disease primarily in one of two ways. The first is to ream out clogged arteries or flatten deposits in the vessels with angioplasty. This procedure does have some risk for heart attack or making the blockage even worse. Many of the blockages return to their original severity within a year.

The second way is to cut away the clogged section or sections of the artery and replace it with a new section or sections of arteries grafted from other places in the body. This procedure is called a coronary artery bypass graft, or CABG. According to a pivotal study published in this prestigious medical journal, CABG, compared with less invasive and risky medical therapy, “appears neither to prolong life nor to prevent myocardial infarction [heart attack] in patients who have mild angina [chest pain] or who are asymptomatic [suffer no pain] after infarction in the five-year period after coronary angiography.”

The failure of standard medical treatments to heal heart patients doesn’t really come as a surprise. Fact is, any treatment that fails to support the circulation throughout your entire body is likely to fail you—and your health—in the long run.

Meanwhile, oral chelation therapy is a potent, safe, inexpensive and virtually risk-free heart and circulation treatment … and recent research suggests it may, in fact, be the single most powerful treatment for CVD.

Click here to read more about Oral Chelation

Silymarin and Silybin from Milk Thistle

In 1968, a group of German scientists discovered the active flavonoid complex silymarin, which provides milk thistle’s medicinal benefits.

Since then, hundreds of studies have been done on silymarin, and it is approved in the German Commission E Monographs (the most accurate information available on the safety and efficacy of herbs) as a supportive treatment for inflammatory liver conditions such as cirrhosis, hepatitis, and fatty infiltration caused by alcohol and other toxins.

Silymarin is used to:

  • Regenerate liver cells damaged by alcohol or drugs
  • Decongest the liver (A liver decongestant stimulates bile flow through the liver and gallbladder, thus reducing stagnation and preventing gallstone formation and bile-induced liver damage.)
  • Increase the survival rate of patients with cirrhosis4
  • Complement the treatment of viral hepatitis5
  • Protect against industrial poisons, such as carbon tetracholoride (a colorless gas that leaks into air, water and soil near manufacturing and waste sites)6
  • Protect the liver against pharmaceuticals that stress the liver, such as acetaminophen and tetracycline1
  • Antidote and prevent poisoning from the death cap mushroom, Amanita phalloides 789

Read more here

Chelation Introduction

Healthy Cardio

Chelation comes from the Greek word “claw,” meaning “to grab,” which is exactly what EDTA does. When a molecule of EDTA travels through the bloodstream and gets near a toxic metal such as lead or mercury, it grabs the destructive particle and binds tightly with it, pulling it out of the membrane or body tissue it was embedded in.

Please click here read today’s article for more information on this health solution.

To your health,
Us Smart Publications

Use of Vitamin C in the Treatment of COVID-19 and Other Viruses

Virus
Vitamin C in Treatment of COVID-19 and Other Viruses

The Orthomolecular Medicine News Service points out that epidemics seem to be on the rise. In a total of 98 epidemics in the 200 years of 19th and 20th centuries, there were 14 epidemics with 1000 or more deaths. However, in the last 20 years, in a total of 63 epidemics, there have already been 11 epidemics with more than 1,000 deaths. 

Be safe, stay well, and be sure to share the important information in this article.

Orthomolecular Medicine Rationale for Vitamin C Treatment of COVID-19 and Other Viruses

Growth Hormone – Essential to Health – Declines With Age

Pituitary Gland

Growth hormone (GH) is involved in a wide variety of activities essential to health, including the repair of damaged tissue in bones, organs and muscles; maintaining muscle mass; insulin sensitivity and burning fat; promoting strong immune defenses; and supporting healthy blood vessels, blood pressure and cholesterol levels.

GH is produced by the pituitary gland, which secretes tiny amounts throughout the day and night in a series of pulses. Total daily GH secretion peaks around puberty and begins to decline by age 21, until, by age 60, most adults, despite the fact that their pituitary is still producing GH, have total 24-hour GH secretion rates indistinguishable from those of younger patients with severely compromised pituitary function.1

Why restore GH secretion to more youthful levels?

Aging adults, even those receiving hormone replacement therapy with DHEA, thyroid, estrogen and/or testosterone, still frequently report fatigue, lethargy, and decreased strength and exercise tolerance. Plus, several recent large population studies show the risk of cardiovascular disease and death is significantly increased in adults whose circulating levels of GH are very low.

Click here to read more . . .

Triage Theory of Micronutrients

serotonin chemistry

In October 2009, Dr. Bruce Ames and his research team from Children’s Hospital Oakland Research Institute in Oakland, California, published the article Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? in the October 2009 issue of the American Journal of Clinical Nutrition.

While some insiders immediately recognized the importance of this paper, it wasn’t until February 2010, when Dr. Ames was interviewed in the nutritional supplement trade publication, NutraIngredients, that his breakthrough article finally got the attention it deserved.

What Dr. Ames and his colleagues accomplished was nothing short of amazing. First, they were able to prove that Dr. Ames “triage” theory for macronutrients—a theory that suggests the body prioritizes the use of scarce micronutrients in favor of short-term survival at the expense of long-term health—was indeed correct. Secondly, they were able to clearly demonstrate that the current recommendations for vitamin K intake needs to be increased to prevent heart disease, osteoporosis, and ensure optimal human health.

Triage Theory Origin

Dr. Ames first presented his triage theory of aging back in 2006. At that time, it was just a theory and Dr. Ames did not have the clinical data to support it. But to him, the theory made perfect sense and he knew it was just a matter of time before he could prove it.

What his triage theory says is, like Robin Hood, when the body requires nutrients for short-term health and reproduction, it robs them from organs that are nutrient rich and of lesser importance in order to sustain major organs that are nutrient poor.

FDA Vitamin K Recommendations Too Low!

The FDA’s RDI for vitamin K is 90 mcg per day. However, that amount is strictly based on what is required for healthy blood coagulation and does not take into consideration the amounts required by the body to process calcium for proper bone building, osteoporosis prevention, and protect the heart from atherosclerosis.

Some scientists are recommending adult daily vitamin K doses for maintaining optimal health as follows:

  • Vitamin K1 (phylloquinone) 240 mcg
  • Vitamin K2 (menaquinone-7) 45 mcg

In addition, it should be noted that these are still on the low end of the vitamin K spectrum. People who get no  vitamin K from their diets might consider dosages at double or even triple these amounts.

For example, Dr. Ames says, “If you’re short of iron, you take it out of the liver before you take it out of the heart because if you take it out of the heart, you’re dead. But the downside is, doing this causes long-term DNA damage, which doesn’t show up as cancer for 20 years.”1

“If you’re deficient for years your body weakens, DNA becomes damaged and you get sick and eventually die.” Dr. Ames adds, “If you want maximum life span, your micronutrient needs must be met throughout life.”

So Ames and his team set out to prove his theory and they chose vitamin K as the first place to start because they already knew vitamin K deficiency is quite widespread.

What they found was truly frightening. When the supply of vitamin K was limited, as it is in the typical American diet, the body utilizes what little it can find to protect critical metabolic functions in the liver. Unfortunately, that leaves other vitamin K-dependent proteins, the ones associated with bone building, cancer prevention, and protecting the heart from atherosclerosis, without sufficient vitamin K to function properly. The result of this leaves the body at risk for developing age-related diseases like cancer, heart disease, and osteoporosis.

Unfortunately, current FDA recommendations for vitamin K (90 mcg/day for adults) are based on levels to ensure adequate blood coagulation, but fail to ensure long-term optimal levels.

From Ames’ triage perspective, much of the population, and patients who are taking warfarin/Coumadin (blood thinners), are not receiving sufficient vitamin K for optimal long-term health.2

“A triage perspective reinforces recommendations of some experts that much of the population, along with warfarin/Coumadin patients, are not getting sufficient vitamin K for optimal function of vitamin K dependent proteins that are important to maintain long-term health,”wrote Dr. Ames.

What you should know about Vitamin K

Vitamin K is a fat-soluble vitamin, meaning it is stored in fatty tissue in the body. Vitamin K is known as the clotting vitamin because without it blood would not clot.

It is important to note, that while Dr. Ames’ study looked at the body’s vitamin K usage as a whole, there are actually two forms of vitamin K, known as vitamin K1 (phylloquinone) and vitamin K2 (menaquinone).

Is Your Multivitamin Supplement Suffering From Nutrient Deficiencies?

Vitamin K1 is found in green leafy vegetables such as lettuce, broccoli and spinach, and makes up about 90% of the vitamin K consumed in the diet. Vitamin K2 accounts for the other 10% and can be found in meat, and fermented food products like cheese, and natto. However, as stated before, most people do not get enough vitamin K (both K1 and K2) from food sources and most multivitamin supplements contain little if any vitamin K.

This deficiency is putting the vast majority of the population at risk for age-related disease like arterial calcification, osteoporosis and bone fracture, and cancer.

  1. Downey, Michael.  The triage theory offers a new look at aging. Natural Foods Merchandiser. Jan. 1, 2007
  2. McCann JC, Ames BN, Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? Am J Clin Nutr. 2009 Aug 19. [Epub ahead of print]

Use N-Acetylcarnosine (NAC) to Prevent Cataracts

Picture of a senile cataract eye

A study published in the American Journal of Therapeutics provides further proof that eye drops containing n-acetylcarnosine, abbreviated as NAC, can slowly reverse existing cataracts and prevent new ones from forming.

This study builds upon NAC’s already impressive clinical track record for the prevention and reversal of cataracts. Since the start of this century, NAC has been used by thousands of individuals to treat age-related eye diseases like cataracts, and macular degeneration.

In this study of more than 50,000 elderly individuals, N-acetylcarnosine topical eyedrops target therapy was demonstrated to have significant efficacy, safety, and good tolerability for the prevention and treatment of visual impairment. In their conclusion, the study’s authors wrote:

“Overall, accumulated study data demonstrate that … N-acetylcarnosine eyedrops, promote healthy vision and prevent vision disability from senile cataracts, primary open-angle glaucoma, age-related macular degeneration, diabetic retinopathy, and aging. N-acetylcarnosine eyedrop therapy is the crown jewel of the anti-aging medical movement and revolutionizes early detection, treatment, and rejuvenation of aging related eye-disabling disorders.”

In a previous long-term study, these same researchers observed the changes in lens clarity over a 6 to 24 month period for 49 volunteers. The average age of the participants was 65, and all suffered from senile cataracts ranging from minimal to advanced opacification (clouding of the lens).Picture of a senile cataract eye

The patients received either a 1% solution of NAC eye drops or a placebo, as two drops twice a day in each eye. The patients were then evaluated after two months and again after six months.

The evaluations consisted of ophthalmoscopy (glare test), stereocinematagraphic (slit-image) and retro-illumination (photography). A computerized digital analysis then displayed the light scattering and absorbing effects of the centers of each lens.

Buy NAC Eye Drops

Here is the outcome after six months

  • 88.9% of the patients who were treated with NAC had an improvement of glare sensitivity (lowest individual score was a 27% improvement, all the way up to a 100% improvement)
  • 41.5% had a significant improvement of the transmissivity of the lens
  • 90% showed an improvement in visual acuity
  • The patients in the placebo group exhibited little change in eye quality at 6 months and a gradual deterioration at 12 to 24 months

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Vitamin K2 is More Important than Calcium for Preventing Osteoporotic Fracture

Bone Density Examples

In human studies, 25 years of research has linked osteoporotic fracture with vitamin K insufficiency. A study published in 1984 found that patients who suffered fractures caused by osteoporosis had vitamin K levels 70% lower than age-matched controls.

This association has been repeatedly confirmed. One recent trial involving almost 900 men and women found those with the lowest blood levels of vitamin K2 had a 65% greater risk of hip fracture compared to those with the highest levels of the nutrient.

In other human research, vitamin K2 has continually shown to be an effective treatment against osteoporosis: A review study of all randomized, controlled human trials of at least 6 months duration that assessed the use of vitamin K1 or K2 to lessen fracture risk identified 13 trials. All but one showed vitamin K reduced bone loss with K2 being most effective, reducing risk of vertebral fracture by 60%, hip fracture by 77%, and all non-vertebral fractures by 81%. And remember, reducing fracture risk is the true measure of bone health.

In a 2-year study of 241 women with osteoporosis, subjects were given either vitamin K2 plus calcium or calcium alone. At the end of the study, women receiving only calcium had lost an average of 3.3% of their lumbar (lower spine) BMD, while those receiving vitamin K2 lost just 0.5%. Women taking K2 plus calcium had one-third the fracture risk of those receiving calcium only.

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