Fibrinogen (a blood clotting protein) levels rise as we get older. And high levels of fibrinogen usually lead to increased platelet aggregation, blood clots, and eventually heart attack or stroke.
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High fibrinogen levels are considered a more dangerous risk factor for heart attack and stroke than high cholesterol. A study of 2,116 men found that those with high LDL (bad) cholesterol but low fibrinogen levels had only one sixth the risk for heart attack than the men with low LDL and high fibrinogen.