Use N-Acetylcarnosine (NAC) to Prevent Cataracts

Picture of a senile cataract eye

A study published in the American Journal of Therapeutics provides further proof that eye drops containing n-acetylcarnosine, abbreviated as NAC, can slowly reverse existing cataracts and prevent new ones from forming.

This study builds upon NAC’s already impressive clinical track record for the prevention and reversal of cataracts. Since the start of this century, NAC has been used by thousands of individuals to treat age-related eye diseases like cataracts, and macular degeneration.

In this study of more than 50,000 elderly individuals, N-acetylcarnosine topical eyedrops target therapy was demonstrated to have significant efficacy, safety, and good tolerability for the prevention and treatment of visual impairment. In their conclusion, the study’s authors wrote:

“Overall, accumulated study data demonstrate that … N-acetylcarnosine eyedrops, promote healthy vision and prevent vision disability from senile cataracts, primary open-angle glaucoma, age-related macular degeneration, diabetic retinopathy, and aging. N-acetylcarnosine eyedrop therapy is the crown jewel of the anti-aging medical movement and revolutionizes early detection, treatment, and rejuvenation of aging related eye-disabling disorders.”

In a previous long-term study, these same researchers observed the changes in lens clarity over a 6 to 24 month period for 49 volunteers. The average age of the participants was 65, and all suffered from senile cataracts ranging from minimal to advanced opacification (clouding of the lens).Picture of a senile cataract eye

The patients received either a 1% solution of NAC eye drops or a placebo, as two drops twice a day in each eye. The patients were then evaluated after two months and again after six months.

The evaluations consisted of ophthalmoscopy (glare test), stereocinematagraphic (slit-image) and retro-illumination (photography). A computerized digital analysis then displayed the light scattering and absorbing effects of the centers of each lens.

Here is the outcome after six months

  • 88.9% of the patients who were treated with NAC had an improvement of glare sensitivity (lowest individual score was a 27% improvement, all the way up to a 100% improvement)
  • 41.5% had a significant improvement of the transmissivity of the lens
  • 90% showed an improvement in visual acuity
  • The patients in the placebo group exhibited little change in eye quality at 6 months and a gradual deterioration at 12 to 24 months

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Omega-6 and Omega-3 Fatty Acids

Omega-3

A balance of omega-6 and omega-3 fatty acids is essential to promoting and maintaining health. According to Artemis Simpoulos, M.D., President of the Center for Genetics, Nutrition and Health in Washington D.C. and co-author of The Omega Plan (Harper Collins, 1998), “The ratio of omega-6 to omega-3 fatty acids in the typical Western diet is betweeen 10-to-1 and 21-to-1, whereas the diet humans evolved on had a ratio of 1-to-1. One of the most important medical findings of recent years is that eating a balanced ratio of EFAs brings your diet back in sync with your genes and helps you experience optimal health.”

Current thinking is that omega-6 and omega-3 fats need to be balanced in the diet at a ratio of 1-to-1 or 2-to-1. And the best way to do that is to supplement your diet with an excellent fish oil nutritional supplement, and/or eat fish several times a week.

Omega-6 and omega-3 fatty acids should be distinguished because they are metabolically and functionally distinct, as well as having opposing physiological functions, says Simpoulos. “Omega-3s and omega-6s work differently in the body. When they’re in balance, they’re both very good. When the omega-6s are in excess, they become bad.”

Here’s what happens: omega-3s produce hormone-like eicosanoids that are anti-inflammatory. These eicosanoids help support normal blood pressure by relaxing the arteries and blood vessels and decreasing blood lipids. They also decrease blood clotting factors and support immune function.

Omega-6s, however, can produce both anti-inflammatory and/or inflammatory and vasoconstricting eicosanoids. To oversimplify just a bit: omega-6s are good for you if you take them in the right amount with omega-3s. However, in the absence of omega-3s they can be very bad indeed.

Too many omega-6s in your diet in the absence of sufficient omega-3s can produce potent inflammatory agents that set the stage for autoimmune diseases such as arthritis, and a host of other health problems.

But the eicosanoids produced by omega-3s help inhibit the production of these inflammatory agents. To clarify further: LA gets made into GLA, then into DGLA and then into either AA (arachidonic acid), which then gets made into inflammatory eicosanoids, or the DGLA gets made into a series of VERY BENEFICIAL eicosanoids that have, among other effects, antiviral and anti-vaso-constrictive effects.

What determines whether DGLA goes to AA or to the beneficial eicosanoids?

Well, low EPA and high insulin will cause DGLA to go to AA (that’s why Americans have such high levels of AA; we make it in our own bodies). If you have good levels of EPA and low insulin (by doing an insulin-smart diet) then your body will NOT make AA from DGLA … instead the DGLA will get made into the beneficial eicosanoids.

So, in a word, to turn omega-6 fats into a positive biological reaction, you take omega-3s! Confusing enough yet?

Even though omega-6 is an essential fatty acid, too much of it can do more harm than good. Insulin encourages the conversion of (omega-6) Gamma linolenic acid (GLA) into arachidonic acid. So does consumption of sugar, alcohol, saturated fats and trans-fatty acids, diabetes, aging, stress, and some prescription medications. Low levels of EPA also strongly encourage the conversion of omega-6 into AA. In essence, everything about the modern Western World diet encourages the conversion of dietary LA into heart disease causing AA! The solution? Reduce your intake of refined carbohydrates and take fish oil!

Read more about Omega-6 and Omega-3 fatty acids here:

Omega-3 Fatty Acids From Fish Oil Protect Your Heart, Brain and Overall Health